The evolution of personalized healthcare and the pivotal role of European regions in its implementation

Background: Personalised Medicine moves at the same pace of data and technology and calls for important changes also in healthcare. New players are at stake, and they are providing impulse to PM. Methodology: We review the conceptual foundations for Personalised Medicine and Personalised Healthcare and their evolution through scientific publications where a clear definition and the features of the different formulations are identifiable. We then examined PM policy documents of the IC-PerMed and related initiatives to understand how PM stakeholders have been changing. Conclusion: Regional authorities and stakeholders have joined the race to deliver personalised care and are driving towards what could be termed as the next Personalised Healthcare. Their role as a key stakeholder in PM is expected to be pivotal.