This work reports the design, fabrication and optical characterization of a micro-reactor array (MRA), consisting of a matrix of transparent wells realized on a opaque silicon substrate, coupled with a CMOS Single-Photon Avalanche Diode (SPAD) array, for bioaffinity assays based on fluorescence markers. The MRA is designed to provide a number of reaction sites in the same chip that can be independently functionalized and monitored, allowing for a fast and all-on chip analysis
A micro-reactor array for fluorescence markers-based bioaffinity assays
Morganti, Elisa;Collini, Cristian;Lorenzelli, Leandro;Borghetti, Fausto;Stoppa, David;Gonzo, Lorenzo
2009-01-01
Abstract
This work reports the design, fabrication and optical characterization of a micro-reactor array (MRA), consisting of a matrix of transparent wells realized on a opaque silicon substrate, coupled with a CMOS Single-Photon Avalanche Diode (SPAD) array, for bioaffinity assays based on fluorescence markers. The MRA is designed to provide a number of reaction sites in the same chip that can be independently functionalized and monitored, allowing for a fast and all-on chip analysisFile in questo prodotto:
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