Atrial fibrillation (AF) is the most frequent supraventricular arrhythmia but despite this its electrophysiologic substrate is still not completely known due to few studies on atrial ectivation during AF in humans. Aim of this study wat to evalutate the spatial and temporal distribution of wavelets circulating throughout the atrial tissue with an extensive mapping of the electrical excitation of the atria during AF. Endocardial mapping of right (RA) and left atrium (LA) during AF was performed in 10 patients (pts) with paroxysmal idiopathic AF. Electrograms were silultaneously recorded in the RA by a basket catheter and in the LA by 2 decapolar catheters positioned in the coronary sinus (CS) and on the septum. AF intervals (FF) in a 10 s period and the morphologic features of AF by Wells' classification for 30 s to quantify the degree of organization of AF were nalywed simultaneously in 10 atrial sites. In the RA the analyzed regions were: high (RHL) and low lateral wall (RLL) , high (RHS) and low septum (RLS), and in the LA: high septum (LHS). low septum (LLS) and the coronary sinus (CS). Different regions of the atria showed different activation pattern. The LS, LP, LHS and LLS showed significantly shorter FF intervals than the right lateral wall; similarly in the same regions a higher prevalence of type I AF was present. although it did not reach a statistical significance. Atrial mapping during AF in these pts showed a non homogenous pattern of activation in different regions of the atria. The septal and right low posterior areas are the regions with the more irregular and disorganised atrial activity

Atrial endocardial mapping in patients with idiopatic atrial fibrillation

1998

Abstract

Atrial fibrillation (AF) is the most frequent supraventricular arrhythmia but despite this its electrophysiologic substrate is still not completely known due to few studies on atrial ectivation during AF in humans. Aim of this study wat to evalutate the spatial and temporal distribution of wavelets circulating throughout the atrial tissue with an extensive mapping of the electrical excitation of the atria during AF. Endocardial mapping of right (RA) and left atrium (LA) during AF was performed in 10 patients (pts) with paroxysmal idiopathic AF. Electrograms were silultaneously recorded in the RA by a basket catheter and in the LA by 2 decapolar catheters positioned in the coronary sinus (CS) and on the septum. AF intervals (FF) in a 10 s period and the morphologic features of AF by Wells' classification for 30 s to quantify the degree of organization of AF were nalywed simultaneously in 10 atrial sites. In the RA the analyzed regions were: high (RHL) and low lateral wall (RLL) , high (RHS) and low septum (RLS), and in the LA: high septum (LHS). low septum (LLS) and the coronary sinus (CS). Different regions of the atria showed different activation pattern. The LS, LP, LHS and LLS showed significantly shorter FF intervals than the right lateral wall; similarly in the same regions a higher prevalence of type I AF was present. although it did not reach a statistical significance. Atrial mapping during AF in these pts showed a non homogenous pattern of activation in different regions of the atria. The septal and right low posterior areas are the regions with the more irregular and disorganised atrial activity
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11582/1594
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