A high resolution Time Correlated Single Pho-ton Counting (TCSPC) image sensor based on sample and hold Time to Amplitude Converter (TAC) pixels and a global ramp voltage is presented. The256x256 array achieves an 8μmPixel Pitch (PP),19.63 % Fill Factor (FF), output volt-age range (0.7 V) and time jitter of 368 ps at10 fps employing an off-chip 14-bit differential Analogue to Digital Converter (ADC). A column-parallel flash ADC is also implemented, allowing coarse 3-bin TCSPC histogramming at 4 kfps for video rate fluorescence lifetime imaging.
A 256x256 SPAD array with in-pixel Time to Amplitude Conversion for Fluorescence Lifetime Imaging Microscopy
Parmesan, Luca;
2015-01-01
Abstract
A high resolution Time Correlated Single Pho-ton Counting (TCSPC) image sensor based on sample and hold Time to Amplitude Converter (TAC) pixels and a global ramp voltage is presented. The256x256 array achieves an 8μmPixel Pitch (PP),19.63 % Fill Factor (FF), output volt-age range (0.7 V) and time jitter of 368 ps at10 fps employing an off-chip 14-bit differential Analogue to Digital Converter (ADC). A column-parallel flash ADC is also implemented, allowing coarse 3-bin TCSPC histogramming at 4 kfps for video rate fluorescence lifetime imaging.File in questo prodotto:
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