Among the physical transfection techniques (used to delivery biomolecules of interest into cells), electroporation generates transient pores in the plasma membrane by applying electrical pulses to suspended cells. Nowadays, alternative microscale approaches are increasingly required. This work presents an integrated microdevice consisting of a gold microelectrode array (MEA) for cell transfection and fluidic channels for controlled single-site delivery of bio-chemical entities.
An integrated platform for single-site cell electroporation
Odorizzi, Lara;Ress, Cristina;Collini, Cristian;Morganti, Elisa;Lorenzelli, Leandro;Coppedè, Nicola;Iannotta, Salvatore;
2010-01-01
Abstract
Among the physical transfection techniques (used to delivery biomolecules of interest into cells), electroporation generates transient pores in the plasma membrane by applying electrical pulses to suspended cells. Nowadays, alternative microscale approaches are increasingly required. This work presents an integrated microdevice consisting of a gold microelectrode array (MEA) for cell transfection and fluidic channels for controlled single-site delivery of bio-chemical entities.File in questo prodotto:
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