Among the physical transfection techniques (used to delivery biomolecules of interest into cells), electroporation generates transient pores in the plasma membrane by applying electrical pulses to suspended cells. Nowadays, alternative microscale approaches are increasingly required. This work presents an integrated microdevice consisting of a gold microelectrode array (MEA) for cell transfection and fluidic channels for controlled single-site delivery of bio-chemical entities.



Titolo: An integrated platform for single-site cell electroporation
Autori: 
Odorizzi, Lara
Ress, Cristina
Collini, Cristian
Morganti, Elisa
Lorenzelli, Leandro
Coppedè, Nicola
Iannotta, Salvatore
mostra contributor esterni 
Data di pubblicazione: 2010
Abstract: Among the physical transfection techniques (used to delivery biomolecules of interest into cells), electroporation generates transient pores in the plasma membrane by applying electrical pulses to suspended cells. Nowadays, alternative microscale approaches are increasingly required. This work presents an integrated microdevice consisting of a gold microelectrode array (MEA) for cell transfection and fluidic channels for controlled single-site delivery of bio-chemical entities.
Handle: http://hdl.handle.net/11582/10033
Appare nelle tipologie:4.1 Contributo in Atti di convegno

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