In the last decade, fundamental advances in the fabrication technology of cell-based microsystems have demonstrated the feasibility to utilize living cell as primary transducer to detect biologically active agents. This screening-based methodology represents an emerging technique and benefits a large area of biomedical applications, ranging from basic research to various fields of pharmacological analyses. In this paper we describe the design implementation, validated by experimental results, of an integrated read-out circuit for field-portable silicon based microsystem designed for multisite monitoring of the physiological state of a cell population
Development of a CMOS multiplexing interface for ISFET array-based microsystems
Lorenzelli, Leandro;
2004-01-01
Abstract
In the last decade, fundamental advances in the fabrication technology of cell-based microsystems have demonstrated the feasibility to utilize living cell as primary transducer to detect biologically active agents. This screening-based methodology represents an emerging technique and benefits a large area of biomedical applications, ranging from basic research to various fields of pharmacological analyses. In this paper we describe the design implementation, validated by experimental results, of an integrated read-out circuit for field-portable silicon based microsystem designed for multisite monitoring of the physiological state of a cell populationI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
